In situ structure and organization of the influenza C virus surface glycoprotein

Influenza C virus contains a single surface Nasal And Bronchial Medications glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, that mediates receptor binding, receptor destruction, and membrane fusion activities.Here, the authors apply electron cryotomography of whole virus together with subtomogram averaging to determine Cowboy Hat the HEF structure and lattice organisation on the viral membrane and they discuss mechanistic implications for virus budding and membrane fusion.